Pakistan Physiological Society

Pakistan Journal of Physiology


Pak J Physiol 2026;22(1)pISSN 1819-270X, eISSN 2073-1183, Volume 22, Number 1 (JanMar 2026)

Chief Editor

Muhammad Aslam

Editors

Muhammad Ayub

Muhammad Alamgir Khan

Associate Editor

Umar Ali Khan

Samina Malik

Assistant Editors

Madiha Imran

Sadaf Mumtaz

Inayat Shah

Adnan Kanpurwala

Editorial Secretary

Muhammad Ajmal

Editorial Office

Room # 126, 1st Floor,

Doctors� Plaza, Opp.

Ayub Medical College, Abbottabad-22040, Pakistan.

Cell: +92-314-5000900

Email: pjp@pps.org.pk

URL: www.pjp.pps.org.pk

Pakistan Journal of Physiology, (Pak J Physiol, PJP) publishes original research papers in all areas of Biological Sciences including but not limited to human and animal Physiology. It is recognised by Pakistan Medical & Dental Council. It is indexed by EMRO Index Medicus, Index Copernicus, Pakmedinet, and Index Pakistan. All articles published, including editorials, letters, and book reviews represent opinion of the authors and do not reflect the official policy of PJP, Pakistan Physiological Society, or the Institution with which the author is affiliated, unless it is specified. All submissions are electronic to be submitted on Open Journal System (OJS). For details, authors should read the Guidelines for Authors published in every issue. Pakistan Journal of Physiology is self-supported by the authors.

The published material is accessible free for research and academic purposes with due citation reference to Pak J Physiol. The publication is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

CONTENTS

EDITORIAL

 

Medical importance of human microbiota

Tehseen Iqbal

1

ORIGINAL ARTICLES

 

Serum cystatin C as a biomarker of acute kidney injury in pre-eclamptic patients

Saqibah Rehman, Tariq Mahmood Ahmad, Asma Hayat, Ayesha Qamar, Syeda Basma Bukhari, Saima Bashir

3

Correlation of urinary neutrophil gelatinase associated lipocalin with erythropoietin in acute kidney injury

Aamir Asmatullah, Ayesha Sardar, Maham Khalid, Rashid Mahmood, Aslam Khan Mohmand, Fatima Munir

6

Antihypertensive effects of ethanolic extract of Trapa Natans seeds IN L-name-induced hypertensive rats

Maria Liaqat, Khadija Mastoor, Muhammad Naveed Mushtaq, Huma Sohail, Salman Haider Shah Hashmi,

Aqsa Arif

9

Protective role of Empagliflozin against methotrexate-induced liver injury

Salahuddin Shaikh, Sheraz Ansari, Farzana Rahim Memon, Farheen Malik, Unshall Memon,

Anjuman Gul Memon

12

Relationship of eating domains with anxiety and physical activity among university students of Lahore

Muhammad Hasnat Agha, Muhammad Adil Agha, Syed Inayat Ali, Saima Bairam, Mahnoor Yasir, Shahid Pervez Shaikh, Afsheen Mansoor, Mudassar Mushtaq Jawad Abbasi

16

Postpartum depression at secondary healthcare level in Northern Pakistan

Nazia Wahid, Zainab Nazneen, Sobia Ali, Hina Iftikhar, Kashmine Mehboob, Arooj Batool

20

Efficacy of oral Tranexamic acid versus placebo in the treatment of epidermal melasma

Jehanzeb Sikandar Rana, Sumyra Saleem, Muhammad Erfan, Sadia Lodhi, Hina Aslam, Mehwish Tayyab

24

Ameliorative effects of melatonin on histopathological changes in lung tissue of nicotine-exposed rats

Shazia Parveen Channar, Sana Kashif, Sheeraz Ansari, Tariq Feroz Memon, Qandeel Abbas Soomro, Huma Abbasi

28

Effect of Bacillus Clausii in combination with phototherapy in the treatment of neonatal hyperbilirubinemia: a quasi-experimental study in a tertiary care hospital

Hina Batool Siddiqui, Abeer Asif, Attia Bano, Saba Mushtaq, Nadia Bashir, Shanzay Nahal

33

Effect of ketogenic diet on leptin level in a depressed rat model

Amber Farid, Muhammad Omar Malik, Syed Murtaza Shah Bukhari, Saadia Anwar, Muhammad Irfan Shereen, Abdul Haseeb, Awais ul Islam, Saif ul Islam, Muhammad Mustafa, Muhammad Mobashar

37

Whole exome sequencing of a Pakistani family segregating autosomal recessive Gaucher disease type I

Muhammad Imran, Maryam Shafaq, Nida Shafi, Amna Mahmood, Syed Khalil Akbar, Shahida Awais,

Syed Irfan Raza

42

Right ventricular function on routine echocardiography as a predictor of short-term outcomes in acute heart failure admissions in a resource-limited tertiary care hospital in Pakistan

Misbah Manzoor, Syed Alishan, Safiullah, Muhammad Aitzaz

46

Comparison of multiple artificial intelligence-models� predictive power in detecting delayed analgesia in emergency department patients

Ayesha Saeed, Muhammad Moeed Azwar Bhatti, Zubia Razzaq, Zainub Saeed

52

Renal function and oxidative stress in doxorubicin-treated wistar rats: Implications for nephrotoxicity

Fazeela Rizwan, Shahnaz Bano Memon, Sehar Khowaja, Asiya Kazi, Ahsan Aslam, Rida Qureshi

58

REVIEW ARTICLE

 

From bite to brain: A deep dive into the rabies virus and its impacts

Babar Mumtaz Malik, Amnah Mutaq Al-Rasheedi, Areeba Asif, Noman Aslam, Maryam Hameed, Muhammad Atif

62

Guidelines for Authors